Texas establishes DPRIT to enhance dementia research and prevention funding

Texas is poised to become a leader in dementia research and prevention with the establishment of the Dementia Prevention and Research Institute of Texas (DPIRT), following a recent Senate Committee on Finance meeting. This initiative, modeled after the successful Cancer Prevention and Research Institute of Texas (CPRIT), aims to accelerate advancements in dementia-related research and treatments.

The oversight committee for DPIRT will consist of nine members appointed by key state leaders, including the governor and lieutenant governor. This committee will be responsible for governance, hiring a CEO, setting grant priorities, and ensuring that research aligns with the institute's goals. Members will primarily include experienced physicians and scientists, alongside family members and caregivers, ensuring a comprehensive approach to dementia research.

DPIRT will award grants to enhance research capabilities across eligible institutions, covering various aspects of dementia, including causes, prevention, treatment, and rehabilitation. Up to 10% of the total grants each fiscal year may focus on prevention strategies to reduce dementia incidence. The initiative also proposes the creation of a new fund, contingent upon voter approval, which would receive $3 billion from general revenue, mirroring CPRIT's funding structure.

To maintain transparency and fairness in grant distribution, strict conflict of interest rules will be enforced, and all proposals will undergo a peer review process. Additionally, DPIRT will be required to submit annual reports and undergo independent financial audits.

The proposed legislation is set to take effect on December 1, 2025, pending voter approval of a constitutional amendment. This initiative follows Texas voters' previous support for CPRIT, which has become the largest state cancer research investment in U.S. history. With DPIRT, Texas aims to replicate this success and address the growing challenges posed by dementia and related disorders, ultimately benefiting families across the state.