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Clinicians: no antiviral for measles; treatment is supportive as some cases require respiratory support

3048443 · April 17, 2025
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Summary

Local pediatricians and physicians described typical measles progression, possible complications including pneumonia and encephalitis, and said there is no specific antiviral — care focuses on symptom management and, for some exposed infants, immune globulin (IVIG).

Local clinicians at the Lubbock Public Health news conference outlined how measles presents, the complications clinicians watch for and how cases are managed because there is no specific antiviral treatment for measles.

Dr. Anna Montanez, a general pediatrician in Lubbock, said: “There is no specific antiviral treatment for measles.” She told reporters that clinical care centers on treating symptoms such as cough, fever, sore throat and conjunctivitis, and preventing complications including pneumonia and encephalitis. Montanez noted a rare, fatal long-term complication — subacute sclerosing panencephalitis — can occur years after infection.

Why it matters: clinicians said measles can cause severe inflammation of the lungs and brain and that respiratory failure from measles-associated pneumonia can require advanced respiratory support. A physician at the conference described respiratory failure as the point at which the lungs can no longer provide sufficient oxygen and said supportive measures range from supplemental oxygen to intubation and ventilatory support while the patient’s immune system recovers.

Use of immune globulin after exposure: speakers confirmed that intravenous immune globulin (IVIG) remains a tool to protect high-risk exposed infants who cannot mount a vaccine response and that it is “highly effective.”

Deaths and underreporting: physicians at the event cited recent mortality linked to the outbreak — two deaths in Texas and one in New Mexico discussed during the conference — and referenced a CDC historical estimate of 1 to 3 deaths per 1,000 measles cases. One clinician noted underreporting in some rural counties because families may manage symptoms at home and not seek testing, which complicates case counts.

Ending: clinicians urged residents to confirm vaccination status and seek medical attention for severe symptoms such as difficulty breathing, persistent high fever or signs of neurological involvement.