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GDC gene-expression API: availability, selection and values endpoints explained
Summary
GDC demonstrated three gene expression API endpoints—availability, gene_selection and values—showing how to construct POST payloads with case UUIDs and Ensembl gene IDs, read top variably expressed genes (example TP53 and KRAS), and retrieve expression matrices in TSV format.
During the webinar Bill demonstrated the GDC’s gene expression API and the three endpoints that underpin the portal clustering tool: availability, gene_selection and values.
He explained how to build cURL POST requests and emphasized payload conventions: case identifiers must be UUIDs (exportable from the cohort builder) and gene identifiers must be Ensembl IDs (gene symbols are not accepted for the API). Bill warned that curly quotation marks (often introduced by Word/PowerPoint) break command lines and advised using straight quotes. He also recommended the…
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