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Board declines to add 3MCC deficiency to Washington newborn screening panel
Summary
After a Technical Advisory Committee review found most screen-detected 3MCC cases are asymptomatic and raised concerns about clinical benefit versus costs, the Board voted unanimously not to add 3MCC to the state newborn screening panel, citing limited benefit, capacity and funding considerations.
The State Board of Health on Jan. 14 voted not to add 3-methylcrotonyl-CoA carboxylase (3MCC) deficiency to Washington’s newborn screening panel after a Technical Advisory Committee (TAC) review and Department staff presentation.
Presenters explained that many infants identified through newborn screening for 3MCC remain asymptomatic, and diagnostic…
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