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Board declines addition of 3MCC deficiency to Washington newborn screening panel
Summary
After Technical Advisory Committee review, the Board concluded 3‑methylcrotonyl‑CoA carboxylase (3MCC) deficiency should not be added to the newborn screening panel because most screened individuals are asymptomatic, costs and program capacity were concerns, and funding would be required before implementation.
The State Board of Health unanimously determined on Jan. 14 not to add 3‑methylcrotonyl‑CoA carboxylase (3MCC) deficiency to Washington’s newborn screening panel following a Technical Advisory Committee (TAC) review.
TAC members presented evidence that most people identified through screening for 3MCC remain asymptomatic and that newborn screening can generate false positives and incidental family…
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