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NHSN trainer outlines ventilator‑associated event rules in case‑study session

National Healthcare Safety Network (NHSN) VAE case-study training · January 7, 2026
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Summary

In an NHSN training, Emily Witt walked participants through case studies clarifying VAE eligibility (location‑based), daily minimum ventilator‑setting rules, the progressive VAC→IVAC→PVAP algorithm, antimicrobial‑day requirements, and specimen‑timing limits affecting PVAP determinations.

Emily Witt, a member of the protocol and training team with the National Healthcare Safety Network (NHSN), led a case‑study session on ventilator‑associated event (VAE) surveillance and said the rules are intentionally standardized to capture potential hospital‑acquired complications.

Witt emphasized that "VAE surveillance is location based, and so all patients in an adult inpatient location are included regardless of the patient's age," explaining that a 16‑year‑old admitted to an adult ICU would therefore be included in surveillance if that unit's monthly reporting plan selects VAE.

The session reviewed how ventilator data are applied: settings documented before admission (for example, in the emergency department) are excluded from inpatient VAE determinations, and when only a single inpatient value is recorded for a calendar day the daily minimum defaults to the lowest value documented that day. Using the example case, Witt showed how those rules produced a daily minimum FiO2 of 60 and a PEEP of 10 for the admission day because earlier ED values are not used.

Witt walked participants through the VAE algorithm's progressive steps and thresholds. She said the increase in the daily minimum PEEP must meet the worsening‑oxygenation criterion of "greater than or equal to three centimeters of water" above the baseline day in a period of improvement; in the first example the observed increase did not meet that threshold and no VAE was identified.

Using two follow‑up case variants, Witt explained IVAC and PVAP determinations. In one variant the group found IVAC was met because temperature or white blood cell criteria and four qualifying antimicrobial days occurred within the VAE window; a coronavirus positive respiratory specimen in that case was outside the VAE window and therefore did not support PVAP. In a separate example Witt noted that even when a qualifying pathogen ("3+ P. aeruginosa") is collected inside the window, an antimicrobial started before the window does not count as a new qualifying antimicrobial day and can prevent IVAC assessment, meaning the event is reported at the VAC level.

Key teaching points highlighted were: VAE surveillance is driven by patient location rather than patient age; ED ventilator settings are not used for inpatient daily minimum calculations; the VAE algorithm is sequential (VAC then IVAC then PVAP); four consecutive qualifying antimicrobial days must fall inside the VAE window and count as "new" agents; and specimen collection dates matter for PVAP eligibility.

The training concluded with participants applying these rules to worksheet examples; Witt thanked attendees for their participation and closed the session.