Wayne County
countyWayne County, Missouri, nestled in the Ozark foothills, offers a blend of natural beauty and small-town charm. As of 2020, the population was 10,974. The county seat is Greenville. Wayne County is known for its outdoor recreational opportunities and scenic landscapes. Wayne County's economy is supported by industries such as healthcare, manufacturing, and tourism. Major employers include Windsor Foods, Clark Mountain Nursing Home, and Greenville Health Care Center. The county also benefits from its proximity to the Mark Twain National Forest and the recreational opportunities provided by Clearwater Lake and Lake Wappapello. Wayne County holds the distinction of being named the UFO Capital of Missouri, along with the city of Piedmont. The county's history dates back to 1818, predating Missouri's statehood, and it was named after General Anthony Wayne. Its rich history and natural attractions make it a unique place to live and visit.
Wayne County, Missouri
- Classification
- County
- Country
- United States
- County
- Wayne County
- Region
- Ozark foothills
- Total Area
- 774 sq mi
- Land Area
- 759 sq mi
- Water Area
- 15 sq mi
- Latitude
- 37.11
- Longitude
- -90.46
- Notable Features
- Clearwater Lake · Lake Wappapello · St. Francis River · Mark Twain National Forest
- Neighboring Areas
- Stoddard County · Bollinger County · Cape Girardeau County · Madison County · Iron County · Reynolds County
- Population (2020)
- 10,974
- Est. Population (2024)
- 10,820
- Median Age
- 48.2
- Median Income
- $43,393
- Poverty Rate
- 25.72%
- Racial & Ethnic Composition
- The racial makeup of the county is 92.8% White, 4.6% Two or More Races, and 1.0% Hispanic.










- Schools
- 9
- Students
- 1,642
- Teachers
- 11
- Student-Teacher Ratio
- 8:1
- School Districts
- Clearwater R-I School District · Greenville R-II School District
- Outdoor Access
- Yes
- Major Recreation Areas
- Clearwater Lake · Lake Wappapello · Sam A. Baker State Park · Mark Twain National Forest
- Parks & Trails
- Sam A. Baker State Park trails · Markham Springs · Mingo National Wildlife Refuge
- Founded
- 1818
- Named After
- General Anthony Wayne
- Historical Significance
- Wayne County predates Missouri statehood and has played a role in the region's development since the early 19th century.
- Key Events
- County created in December 1818 · Relocation of Greenville in 1941 due to Lake Wappapello construction · Designated as UFO Capital of Missouri in 2023
