JCVI researcher describes Forensic Microbiome Database and evidence that bacterial profiles can indicate sample origin

Feb 9, 2026

Lauren of JCVI reported that bacterial profiles from human microbiome samples—analyzed with 16S rRNA sequencing and machine learning—often cluster by geographic location; the team launched a public Forensic Microbiome Database (FMD) with nearly 14,000 samples to support geosourcing and future forensic use-cases.

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Lauren, a researcher at JCVI, presented results from a National Institute of Justice-funded project that uses bacterial profiles from 16S rRNA sequencing to predict geographic origin and support forensic investigations. The work, now in its second year of a two-year NIJ award, produced a publicly accessible Forensic Microbiome Database (FMD) designed to let researchers and practitioners compare new samples against a broad set of publicly available data.

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