CDC: genome sequencing and NARMS/PulseNet faster outbreak detection
CDC officials credited transitions to whole‑genome sequencing and tighter NARMS–PulseNet integration with earlier detection of smaller and geographically dispersed outbreaks, citing specific use cases including establishment of azithromycin breakpoints for Shigella and a Salmonella outbreak linked to moringa powder with NDM‑1.
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Dr. Gwen Biggerstaff said that PulseNet’s shift from pulsed‑field gel electrophoresis to whole‑genome sequencing (WGS) and improved integration with the National Antimicrobial Resistance Monitoring System (NARMS) have been transformational for outbreak detection.
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